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While traumatic tears are more common in younger athletes, degenerative meniscus tears frequently occur in adults over 40 and are often associated with early osteoarthritis

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PDGF signals through two cell-surface tyrosine kinase receptors, PDGFR and PDGFR, and regulates many biological functions including angiogenesis, by promoting vessel maturation and recruitment of pericytes and by inducing upregulation of VEGF [141]

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