What This Means Practically For patients with Type 2 diabetes, these findings have practical implications: First-line treatment recommendation: Major diabetes guidelines now recommend GLP-1 agonists as first-line treatment (alongside or instead of metformin) for patients with established cardiovascular disease
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Despite the positive results, due to the limited number of included studies, further randomized controlled trials are needed to investigate the safety and efficacy of SGLT2i and GLP-1RAs as first-line treatment options for patients with T2DM at low cardiovascular disease risk, particularly when compared to metformin
What benefits do individuals experience from GLP-1 treatments
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