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They found that for FDA approved GLP-1s for weight loss, liraglutide (Saxenda) and semaglutide (Wegovy), the percent of side effects reported was as follows: Nausea: 42.2% Diarrhea: 21.9% Vomiting: also 21.9% Constipation: 8.4% They report that although the incidence of side effects were similar among medications, semaglutide had the greatest risk of nausea, diarrhea, and vomiting, whereas liraglutide had the greatest risk of upper abdominal pain

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[114] randomized subjects to semaglutide or placebo to observe the change of liver fat from baseline to week 48, and found that semaglutide significantly reduced hepatic steatosis, improved liver enzymes and metabolic parameters, and had a positive effect on the diagnosis and treatment of NAFLD compared with placebo

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Contraindications Do Not Use If You Have an active nasal infection, severe congestion, or recent nasal surgery Have a known hypersensitivity to NAD+ or any inactive ingredient Have uncontrolled hypertension Are pregnant or breastfeeding (safety not established) Warnings and Precautions Proper administration: Follow your providers instructions for priming, dosing, and frequency Avoid sharing the nasal spray device to prevent cross-contamination Nasal irritation: Prolonged use may cause dryness, crusting, or nosebleeds Store as directed typically refrigerated Common Side Effects Nasal burning, irritation, or stinging Sneezing and runny nose Mild headache Unpleasant taste Dryness of the nasal passages Seek Medical Attention For Persistent nosebleeds Signs of allergic reaction Severe or worsening nasal irritation References Sermorelin (Compounded) Sermorelin acetate is a growth hormone-releasing hormone (GHRH) analog that stimulates the bodys own pituitary gland to produce and release growth hormone

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