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In the model cytosolic GSH has three fates: it is transported into the blood, there is a net flux to GSSG, and 0.2% is removed per hour corresponding to detoxification reactions and excretion into the bile

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In the initial stages of drug-induced deafness, the imbalance of redox reactions activates intricate signaling pathways that serve to safeguard cells or facilitating orderly apoptosis (Zong et al

497 Similarly, caregivers who are women may experience slightly higher levels of burden, impaired mood, depression and impaired health than do caregivers who are men, with evidence suggesting that these differences arise because female caregivers tend to spend more time caregiving, assume more caregiving tasks, and care for someone with more cognitive, functional and/or behavioral problems