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Figure 6 Having demonstrated that metformin treatment significantly inhibits oxidative phosphorylation in both in vitro and ex vivo models of rectal cancer, the effect of metformin on histologically-confirmed normal rectal tissue biopsies ( n =12, median age of 41.5 y) taken from non-cancer patients was assessed in real-time using the Seahorse XFe analyser

However, diagnosing medical conditions is not in a dietitians scope of practice, so using ICD-10 codes has to be done carefully

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Any elderly patient experiencing new or worsening neurological symptoms despite B12 treatment should be referred back to their GP for reassessment, as alternative diagnoses must be considered

Never reuse or share needles or syringes