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We assume that this corresponds to the maximal analgesic effect of L838,417 experimentally observed ( Y max 31%, Fig

If a patient takes more medication than is recommended, significant side effects such as renal failure or blood poisoning may appear

Following single and repeat doses from 6 to 20 mcg/kg over 6 weeks, gross necropsy revealed no adverse organ changes

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J Crit Care 26(2):225

2.4.5.2 Liquid chromatography-mass spectrometry analysis conditions The analyzing instrument was a liquid-mass spectrometer system consisting of ACQUITY UPLC I-Class plus ultra-high performance liquid tandem high-resolution mass spectrometer