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These medications mimic the glucagon-like peptide-1 (GLP-1) hormone, which naturally helps control appetite, slow digestion, and regulate insulin response

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Having ready-to-drink shakes or pre-portioned protein powder makes it easy to hit protein goals

Considerations for specific populations Despite the adherence improvement and convenience of GLP-1 patches, they may not be the best option for some people, including: Elderly patients usually have frail skin, making it challenging to apply and remove the transdermal patch

In the Phase 2 NEJM trial (2023), participants on 12 mg lost an average of 24.2% of body weight at 48 weeks

Given that the glucose-lowering effect of metformin is so strong and is independent of incretin signalling, it might be difficult to detect the beneficial effect of metformin on the incretin axis in human studies