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In such cases, the focus should shift to investigating potential underlying causessuch as myeloproliferative disorders, liver disease, or renal dysfunctionrather than attributing symptoms to the elevated B12 itself

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Predominantly, the ECM consists of proteoglycans, glycoproteins, various matrix proteins (such as SPARC/osteonectin, OPN/SPP-1, and THBS/TSP, which are abundant in cysteine residues), and structural proteins (including fibrillin, collagen, and laminin) [54]

All calculations should be independently verified

They should be able to continue your treatment at your current dose rather than restarting from 2.5 mg

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