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Partial least squares-discrimination analysis (PLS-DA) and the heatmap showed a clear classification of the metabolomes between four groups ( Figures 2A, B )

GPC, gel permeation chromatography

16, 11281141 10.1021/acschembio.1c00255 [DOI] [PMC free article] [PubMed] [Google Scholar] 69.Takata T., Jung M., Matsunaga T., Ida T., Morita M., Motohashi H.et al

A 2.0 mg dose was approved in 2024 for additional glycaemic control

Quantitative Real-time PCR RNA extraction and quantitative real-time PCR were performed according to our previously reported method [27]