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The GRAS determination was likely based on the compound's limited systemic absorption (when ingested), short plasma half-life, and lack of acute toxicity signals in the Phase 2b obesity trial

Because AOD9604 remains unapproved by the FDA and is banned by WADA, its critical to understand both the legal risks and potential safety concerns before considering its use

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Takeaway Subcutaneous injection is a method of administering medication into the fatty tissues

Clinical trials confirmed no effect on serum IGF-1 levels, no negative effect on carbohydrate metabolism, and no anti-AOD-9604 antibodies detected in any participants

While the peptide does not increase IGF-1, caution is warranted given the theoretical relationship between growth factors and cancer progression