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A human observational study measured DSIP-like immunoreactivity, meaning DSIP-related biological markers, in Alzheimers disease and frontotemporal degeneration

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In conclusion, our findings reveal that epithelial-derived BDNF prevents macrophage inflammation by directly targeting TLR4 and highlights BDP-12 as a potential therapeutic agent for acute inflammatory diseases

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doi:10.1016/j.otsr.2023.103737 Berzolla E, Sundaram V, Strauss E