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By potentially reducing the presence and impact of senescent cells, FOXO4-DRI might thereby restore tissue homeostasis and reduce biomarkers of cell aging

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Targeting the Copper Transport System to Improve Treatment Efficacies of Platinum-Containing Drugs in Cancer Chemotherapy

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Expression of a different set pectinases in the early stage of infection likely allows the pathogen to colonise tissues in a more subtle manner that does not trigger immunity (Snchez-Vallet et al., 2015)

However, neurotrophins have had little success in clinical trials directed at neurodegenerative diseases due to their poor pharmokinetic profile and large molecular weight that significantly impedes penetration of the BBB [61,62]