Retatrutide is an investigational triple incretin agonist (GLP-1, GIP, glucagon) not yet licensed by the MHRA or EMA in the UK
Women who have used Depo-Provera and subsequently been diagnosed with brain tumors are filing lawsuits against Pfizer (the manufacturer), alleging that the company failed to adequately warn about the risks associated with the drug
These rates were highly correlated with baseline BMI and included discontinuations for perceived excessive weight loss, Lilly said in a press release
The Phase 2 trial published in the New England Journal of Medicine confirmed what many women suspected: they respond to this drug in ways that are meaningfully different from men
"What may be happening, and we don't know for sure, is that when you stop them, your body's left in a GLP-1 deficit which has a major impact on the satiety signal going to the brain," says Whyte
Wegovy, Zepbound, Saxenda, and Foundayo are all approved as weight loss medications for the following people with a demonstrated medical need to lose weight