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At the same time, the complexity of the GLP-1 receptor signaling pathway demands preclinical models that are both reliable and precise

Based on data derived from our previous study [8], inclusion of 16 participants was calculated to provide at least 90% power (at = 0.01 to allow for subgroup comparisons) to detect a 20% difference in glucose iAUC 0120min between metformin treatments and the control

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