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10.1016/j.tem.2019.03.003 17 BersukerK.HendricksJ
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Molecular modeling suggested that AEDG may bind to histone H1 regions that interact with DNA, providing a proposed epigenetic mechanism for changes in neurogenesis-related gene expression and protein synthesis
It stimulates glucose uptake, increases fat metabolism, and boosts mitochondrial function
[3] [4] According to the MHRA-approved Summary of Product Characteristics, the formulation also contains several inactive excipients that serve specific pharmaceutical purposes: Disodium phosphate dihydrate provides buffering capacity to maintain pH stability Propylene glycol acts as a co-solvent and stabilising agent Phenol functions as an antimicrobial preservative Water for injections serves as the vehicle for the solution Hydrochloric acid and/or sodium hydroxide may be used for pH adjustment These excipients are standard pharmaceutical ingredients used in injectable medications and are present in carefully controlled quantities to ensure product stability, sterility, and patient safety
