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It acts simultaneously on glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors, producing significant reductions in body weight and improvements in glycaemic control

In the clinical trial, researchers found that many participants crossed below the obesity threshold entirely

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Similarly, in the SYNERGY-NASH study (Table 3), improvement of at least one fibrosis stage without worsening of MASH was almost doubled with tirzepatide treatment than with placebo [5]

This enhancer may enter breast milk, and its effects on infant gut development are unknown