In this context, glucagon-like peptide-2 (GLP-2) and its sister molecule glucagon-like peptide-1 (GLP-1) are of particular interest, as being critically involved in hepatic lipid homeostasis 5,6
- An oral formulation also showed activity: 7.6% placebo-adjusted weight loss at 36 weeks
Retatrutide represents the most effective weight loss medication in clinical development, showing superior efficacy to both semaglutide and tirzepatide while maintaining comparable safety profiles
The report itselfnot a marketing badgeshould be treated as the source record
And our recommendation is to look at the evidence, not the headlines, where when helping patients really understand the risks here
When beneficial gut bacteria ferment these fibers, they produce short-chain fatty acids (SCFAs), particularly butyrate