This safety consideration matters because post-cholecystectomy patients experience continuous bile flow rather than meal-triggered releasea change that can influence medication tolerability and metabolic response
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However, urgent medical advice should be sought if any of the following occur: Severe or persistent gastrointestinal symptoms : Intractable nausea, vomiting (especially if unable to tolerate fluids), severe abdominal pain, or signs of bowel obstruction require immediate assessment to exclude surgical complications such as stricture or gastric leak (sleeve-specific complications)
Peer-Reviewed Citations Manning MC, et al
