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High prevalence of insulin resistance is suggested in patients with PD ranging from 50 to 80% and type 2 diabetes is associated with an increased risk of PD (151)

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The structure-functional properties of these 5 specific viral-hijacked host cellular factors, their ultimate pathophysiological consequence(s) due to virus-induced HMRD in acute COVID-19 and during long-COVID, the persistent virus-free PASC disease state, is comprehensively described below

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