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Here, we provide a concise overview of the core physiology of GLP-1 secretion and action, and the role of the peptide in human health, disease and therapeutics
Rapid weight loss associated with tirzepatide therapy may contribute to orthostatic hypotensiona drop in blood pressure upon standing
Avoid psyllium husks or glucomannan on days when nausea is prominent, as their volume-expanding properties can intensify that feeling
Synovitis worsens, matrix components are destroyed, and apoptosis occurs as a result of oxidative stress-induced mitochondrial and nuclear DNA damage, lipid peroxidation, changes in cellular signal transduction and transcription, and epigenetic transcription factors (Marchev et al., 2017)