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Safety issues of tirzepatide (pancreatitis and gallbladder or biliary disease) in type 2 diabetes and obesity: A systematic review and meta-analysis

23 Tirzepatide treatment was associated with a significantly reduced annual decline in eGFR, with a 3.7 mL min 1 1.73m 2 per year difference (95% CI, 2.4 to 5.1)

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In contrast, other PTs were less frequently reported, and less common conditions, such as cholelithiasis obstructive and pseudocholelithiasis, had very few or no associated reports