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doi: 10.1016/j.biopha.2020.110923

Focal adhesion- and IGF1R-dependent survival and migratory pathways mediate tumor resistance to mTORC1/2 inhibition

Additionally, their encoded antioxidant enzymes could be promising targets for preventive and future individualized therapeutic strategies

Two ubiquitin ligases, MAFbx and MuRF1, have previously been shown to be rapidly induced in multiple models of muscle atrophy, including the TNF--induced muscle wasting model [14, 32]

It forms the structural framework of the skin, providing firmness, elasticity, and hydration

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