Mitochondrial dysfunction and oxidative stress are often implicated in progressive neurodegenerative disorders such Alzheimers disease and Parkinsons disease and in damage secondary to TBI.5,6 Additionally, new research both in vitro and in mice has suggests that methylene blue may reduce neuronal apoptosis and improve blood-brain barrier integrity.7 One randomized, blinded, placebo-controlled trial evaluated the effects of methylene blue 10mg/kg administered intraperitonially to mice and rats immediately or 24 hours post ischemic stroke
Safety Takeaway: While the evidence from controlled human trials suggests a manageable adverse event profile, the products full extent of long-term safety, especially regarding chronic and rare side effects, remains undetermined until the completion of ongoing large-scale clinical programs and subsequent regulatory review and approval
Your practitioner will set realistic expectations at your consultation
Your BHRC provider will build the right protocol based on your injury, goals, and health history virtually or in person
Mechanisms of oxidative stress have been implicated in the pathogenesis of psychiatric disorders (47)
See our comparison of injectable vs oral peptides for more context
