4.2 Ferroptosis and rheumatoid arthritis Rheumatoid arthritis (RA) is the typical autoimmune disease that primarily targets the synovial membrane of the joints, resulting in the synovium transforming into a hyperplastic and invasive tissue that destroys cartilage and bone (128)
Red Blood Cell Formation: Adequate B12 levels are essential for red blood cell production, guarding against anemia and promoting efficient oxygen transport throughout the body
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On the other hand, the orexigenic signaling via orexigenic peptides (MCH and orexin A and B neuropeptides) results in increased food intake and decreased energy expenditure
Emotional sensitivity Increased emotional responsiveness or mood fluctuations may occur as hippocampal connectivity changes
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