Intraperitoneal administration of high doses of polyethylene glycol (PEG) causes hepatic subcapsular necrosis and low-grade peritonitis with a rise in hepatic biomarkers
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Experimental mice got injections of the peptide 5 times a week, and the results showed that it suppressed the formation of neoplasms, decreased lungs metastases by 1,6 times, multiple tumors by 2 times, 3,7-fold increase of mice without breast tumors and decrease of mice with 6 or more tumors by 3 times
Seminars Immunol
Small molecules inhibiting Keap1Nrf2 proteinprotein interactions: a novel approach to activate Nrf2 function