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Pulsatile GH signals also activate organ-specic second messenger signaling pathways, such as the Signal Transducer and Activator of Transcription 5B (stat5B) in the liver, with subsequent induction of specic genomic responses in relevant target tissues

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[DOI] [PMC free article] [PubMed] [Google Scholar] 134.Longo V.D., Kennedy B.K

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Its sequence is Aib-His-D-2-Nal-D-Phe-Lys-NH2 , incorporating non-standard and D-configured residues that are central to its molecular identity