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Strong Cardiovascular & Renal Protection Evidence continues to grow: - Reduced risk of major adverse cardiovascular events (MACE) - Lower incidence of heart failure and atrial fibrillation - Protective effects in kidney disease and high-risk populations These benefits often extend beyond weight loss alone, suggesting direct biological effects

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NADPH donates the electrons and becomes oxidized to NADP +

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Some individuals view lower doses as a way to support short- or medium-term metabolic goals rather than committing to higher doses long term