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Tirzepatide (Mounjaro, Zepbound) is a related but distinct medication that acts as a dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor co-agonist

The present state of GLP-1 therapeutics demonstrates considerable progress from first-generation short-acting agents to advanced long-acting analogues and innovative oral formulations

Amneal launched its generic in late November 2024

[15] mhra.gov.uk), contributing to ongoing medication safety monitoring

Although retatrutide is not yet available outside of clinical trials, understanding how to manage its side effects is relevant for trial participants and for healthcare professionals preparing for its potential future availability

doi:10.1056/NEJMoa2301972