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These include reducing oxidative stress, decreasing neuroinflammation, promoting neuronal survival, and enhancing synaptic plasticity

Our understanding of the long-term safety of GLP-1 agonists remains limited, a concern that is particularly pertinent for chronic conditions such as pain and headaches

As the therapeutic pipeline continues to expand from GLP-1 receptor agonists to engineered proteins and advanced drug-device combinations, the number of molecules that cannot tolerate traditional sterilization conditions is expected to grow

Regenerating theories in developmental biology

Funding There is no funding associated with this project

The oxidation-generated reducing equivalents accumulate as cytosolic NADPH produced by the pentose phosphate pathway, and mitochondrial NADH, produced by 2-oxo acid dehydrogenases