tirzepatide semaglutide weight loss vs for Tirzepatide outperformed semaglutide weight-loss drug

Elbadawy NN, Saad MA, Elfarrash S, Ahmed MAE, Abdelkader NF (2025) The GLP-1 agonist semaglutide ameliorates cognitive regression in P301S tauopathy mice model via autophagy/ACE2/SIRT1/FOXO1-Mediated Microglia Polarization

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Once GLP-1s are understood as reward modulators rather than just as appetite suppressants, it explains their wider applications

When the drug turns hunger down, thirst goes with it

Function declines faster

Acta Biomed