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In a model of non-ischemic HF in dogs (tachycardiomyopathy induced by pacemakers), IV infusion of GLP-1 increases left ventricular (LV) contractility (LV dP/dt increased by 98%, stroke volume by 102%, and cardiac output by 57%) and decreases LV end-diastolic pressure, heart rate, and systemic vascular resistance

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Symptoms present, workup pending: The patient presents with pain, tingling, or numbness attributable to diabetes

Instead of a quick note that disappears, GLP-1 medications (like semaglutide) are engineered to be long-lasting

They work alongside nutrition and physical activity

Common side effects include nausea, bloating, constipation, fatigue, and headaches