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Quick answer: BPC-157 acts locally to drive angiogenesis and site-directed tissue repair, while TB-500 (thymosin beta-4) acts systemically to promote cell migration

This may be due to their proposed actions on distinct but converging regulatory circuits

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Cell Metab 16(4):487499 Stewart C, Estrada A, Kim P, Wang D, Wei Y, Gentile C et al (2017) Regulation of IRE1alpha by the small molecule inhibitor 4mu8c in hepatoma cells

No human liver-disease trial was identified

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