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It's important to note that while creatine can increase serum creatinine levels, this does not typically indicate kidney damage in healthy individuals

Rare cases of severe anaphylactic reactions have been reported with IV use

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The induction of p70S6K1 phosphorylation was abolished when cells were treated with both BMS-754807 and U0126 (Lane 4), indicating that suppression of MEK1/2 abolishes BMS-754807-induced p70S6K1 phosphorylation

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It functions as a potent vasodilator, modulates smooth muscle activity in the gastrointestinal tract, and participates in neurotransmission in the central and peripheral nervous systems (Lelievre et al., 2008)