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Patients who started a GLP-1 were approximately 43% less likely to progress to Stage IV disease than patients who started a DPP-4 inhibitor, with a hazard ratio of 0.57 (95% confidence interval 0.46 to 0.71)

Thus in addition to increasing GLP-1 concentration, recent research shows that it also lowers insulin concentration and stabilizes ghrelin levels

doi: 10.1007/s11027-024-10126-4 192 NemadodziL

R.TranQ.DillinA.ZoncuR.et al (2017)

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Comparing it with other therapies helps doctors better understand its value