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Game Ready System Comment: We received a comment recommending CMS evaluate and approve the Game Ready System manufactured by Avanos Medical, Inc., under our non-opioid treatment for pain relief separate payment policy

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578 Pharmacological treatments include cholinergic agonists, such as bethanechol, to stimulate detrusor muscle contraction, antimuscarinic agents, such as oxybutynin or tolterodine, for overactive bladder symptoms, and beta-3 agonists, such as mirabegron, to relax bladder smooth muscle during the storage phase

These concerns become especially relevant given the shipping delay complaints documented for some ProRx-supplied providers