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In addition, acting specifically on GABA A , GABA B and/or the glycine receptor, it produced depressive activity [60]

Cytochrome bd biosynthesis in Bacillus subtilis : characterization of the cydABCD operon

NNMT acts as a primary metabolic gatekeeper, predominantly active in fat tissue and liver cells, where it methylates nicotinamide (NAM) using S-adenosyl-L-methionine (SAM) as a methyl donor

2007, titled Insomnia, serotonin and depression, of 100 healthy volunteers (50% male, 50% female) found significant links between serotonin dysregulation and sleep disturbances, with 85% of participants reporting sleep issues

doi: 10.2460/javma.2001.218.48

You may see vitamin B12 listed on nutrition labels as cobalamin, or cyanocobalamin