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In short, DSIP doesnt knock you out like a sleeping pill

NNMT (nicotinamide N-methyltransferase) is the enzyme 5-Amino-1MQ inhibits, and tissue expression varies significantly across organs: adipose tissue shows 812 higher NNMT activity than skeletal muscle, which is why subcutaneous injection near adipose depots produces localised effects rodent models couldn't predict

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The side effects we occasionally see in clinic are mild and typically transient

On the other hand, Ozempic only comes as a once-weekly injection

Tables 1 and 2 summarized the details of the study along with the glucose-lowering effects of tirzepatide as compared to insulin glargine