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The overexpression of antioxidant molecules such as GSH and SOD2, or chaperones such as Hsp70 has proved to be a successful experimental approach in brain diseases, including PD

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Most of the oxygen utilized by the body is completely reduced to water in a single step at the terminal cytochrome of the mitochondrial oxygen transport chain

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Importantly, the genetic and pharmacological inhibition of MT-1G enhances the anticancer activity of sorafenib in vitro and tumor xenograft models (Sun et al., 2016a)