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Doses start at 0.25 mg weekly, increasing every 4 weeks until reaching a maintenance dose of 2.4 mg weekly, if tolerated

10.1016/j.yjmcc.2018.07.250 87 LiR.WangX.WuS.WuY.ChenH.XinJ.et al (2019)

In practice it is sold domestically only as an unregulated "research chemical" labeled not for human consumption, meaning purity, sterility, and labeled concentration are not verified by any regulatory body

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Effica Health is preparing to launch virtual, clinician-led menopause care in Alberta and Ontario, beginning with a friends-and-family group to refine the care model before opening to a wider audience

Overview of Linzess/Constella Linzess (Linaclotide) was initially approved by the U.S