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Use of nasal tanning sprays that are linked to skin cancer and other health problems is on the rise, warns The Chartered Trading Standards Institute (CTSI)

doi: 10.1038/jhh.2010.13 382

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Based on the here-presented biochemical, structural and computational evidence, we propose that arGSTs utilize a GSH-dependent Brnsted base mechanism for conversion of the semi-stable LDOX product flavan-3,3,4-triol ( 4 ) or flavan-3-on-4-ol ( 7 ) into flav-2-en-3,4-diol ( 8 -B4), the 4-hydration species of cyanidin ( 8 ) (Extended Data Fig