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Additionally, EVs derived from steatotic hepatocytes or lipid-laden muscle cells have been shown to carry specific lipid cargo (e.g., ceramides) and microRNAs that can be delivered to recipient cells, such as vascular smooth muscle cells, promoting their phenotypic switch to a pro-calcific, pro-inflammatory state, thereby accelerating atherosclerotic plaque maturation and instability (101, 102)

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Blood Testing for Vyvanse Blood testing can also detect Vyvanse and its metabolites, but it is less commonly used than urine testing

Hyperinsulinaemic hypoglycaemia and diabetes mellitus due to dominant ABCC8/KCNJ11 mutations