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World Psychiatry 21 , 124132 (2022)

The Bottom Line Yesterday's advisory panel vote signals a shift in the regulatory landscape for peptide therapies, but it changes nothing for consumers today

All authors were involved in the drafting and review of the manuscript

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These features overlap with the well-known ABCDE warning signs of skin melanoma: A symmetry B order irregularity C olour variegation D iameter larger than 6 mm (often) E volving size, shape or surface What it feels like Most early oral melanomas are painless