Its half-life is approximately five days, meaning it takes about five days for half the dose to be eliminated from the body
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This could lead to either insufficient glucose control or potentially an increased risk of adverse effects such as nausea, vomiting, or hypoglycaemia (particularly in patients taking concomitant insulin or sulphonylureas)
doi:10.1177/1756287211398255
M.DiazR.Garcia-PerezL
With disease progression, iron depletion in oligodendrocytes may impair myelin and, ultimately, axonal integrity in the white matter, which is believed to play a crucial role in chronic progressive MS [189]