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Temporal anchoring language was included to distinguish current, historical, and future-referenced observations
GLP-1 drugs can offer real benefits for runners, especially those managing chronic conditions
Notably, given that SGLT-2 is expressed in the brain, which is consistent located with enhanced cFos expression induced by SGLT-2is, we hypothesize that SGLT-2is may cross the BBB via receptor-mediated transcytosis
However, more research is needed to fully understand this concept
Dont Be Afraid to Make Alterations 4
Combination therapies that engage complementary mechanisms of action offer a rational strategy to enhance efficacy while minimizing toxicity
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