In addition, considering that thyroid disorders are common in some metabolic diseases such as DM and obesity, we conducted this study
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General skincare measures can help support skin barrier function and reduce sensitivity: Moisturise regularly using fragrance-free, hypoallergenic emollients to maintain skin hydration, particularly if dryness accompanies weight loss Avoid harsh skincare products containing alcohol, strong fragrances, or exfoliating acids, which may exacerbate sensitivity Use broad-spectrum SPF 30+ sunscreen daily as a general skin protection measure, and limit prolonged sun exposure Wear loose, breathable clothing to minimise friction against sensitive skin areas Apply a cool compress to injection site reactions to help reduce localised redness or discomfort Maintain a balanced diet in line with the NHS Eatwell Guide
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Multiple protein feedings ensure amino acids remain available throughout the day
The availability of retatrutide will depend on the completion of trials and FDA approval, which could take some time
