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Autoantibody response to human MOG (1-125) has been observed in induced experimental autoimmune encephalomyelitis (EAE) in DA and Lewis rats, C57/BL6 and SJL mice, and common marmoset

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Its important for patients and healthcare providers to engage in open dialogue about side effects, as managing these early in the course of treatment can significantly impact adherence and overall treatment success

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although albuminuria is a clinically meaningful biomarker and treatment target, it remains a surrogate endpoint and does not, by itself, prove reduction in kidney failure or need for kidney replacement therapy

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