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Clinical Update 3/09/2026 Eggshell Membrane for Knee Pain A new study tested whether eggshell membrane extract can ease pain and stiffness in knee osteoarthritis
DISCLOSURES The authors report no relevant financial relationships which, in the context of their contributions, could be perceived as a potential conflict of interest
The formulation was constructed by encapsulating GYY4137 within liposomes and coating the surface with Eudragit S100, a well-established pH-sensitive polymer that dissolves at pH 7 and is widely recognized for colon-targeted delivery due to its safety and biocompatibility [53]
In this case series, patients reported: Rapid symptom relief (fatigue, brain fog, pain, GI symptoms) Improved dysautonomia and food tolerance Sustained benefit, even in non-obese, non-diabetic patients Minimal side effects at low doses Many experienced weight normalization due to reduced inflammation
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