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Several laboratory tests should be performed prior to treatment with cyanocobalamin, including serum vitamin B12, folate, iron, hematocrit, and reticulocyte count

Curr Neuropharmacol 2016;14(8):857-865

Yoon IY, Kripke DF, Elliott JA, Youngstedt SD, Rex KM, Hauger RL

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Dosing tiers: The approved Vyleesi dose is 1.75 mg

Patients with pernicious anaemia or complete malabsorption typically require lifelong treatment at standard intervals, while those with partial malabsorption may have variable needs