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Excretion Renal elimination is the primary route for GLP-1 RA clearance (23)

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Phentermine monotherapy produces a total weight loss of 10% or more with a number needed to treat of 6 compared with lifestyle interventions alone

Red flags requiring urgent medical attention include severe, persistent abdominal pain (which may radiate to the back), repeated vomiting, inability to keep fluids down, or reduced urine output

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