Harris-Pincus told us, This supplement probably wont harm most people, except for their wallets. There are a plethora of supplements claiming to act like a natural Ozempic, she added, and its unlikely they will result in any real, sustained weight loss. In order to see long-term results with overall health, Harris-Pincus emphasized the importance of permanent diet and lifestyle changes. Harris-Pincus explained, for example, that eating fiber rich foods can stimulate natural GLP-1 and help keep us full. She also noted that its unlikely that a supplement will have a more significant effect than a high protein and high fiber diet
Unlike GLP-1 agonists, the changes are compositional rather than scale-weight driven: patients may not lose significant total body weight but will show meaningful reduction in waist circumference and visceral fat volume
Crookshank, Effect of Ammonium Salts on the Production of Ovine Urinary Calculi, Journal of Animal Science , Volume 30, Issue 6, June 1970, Pages 10021004, Jeffrey M, Duff JP, Higgins RJ, Simpson VR, Jackman R, Jones TO, Mechie SC, Livesey CT
L.WildenthalK.ChapmanC
The loss of the amino-terminal region of Group VIA-2 phospholipase A 2 resulted in a more active enzyme which accelerated membrane phospholipid destruction
But this is correlation, not causation